DEVELOPMENTAL PSYCHOLOGY
ADULTHOOD PHYSICAL COGNITIVE AND SOCIAL DEVELOPMENT
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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muscle weight increases
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memory loss increases
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temperature control is difficult
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the biological clock speeds up
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Detailed explanation-1: -Aging promotes cellular senescence and impairs mesenchymal stem cell (MSC) differentiation in subcutaneous adipose tissue. These changes diminish adipocyte function by reducing preadipocyte maturation, restrict adipocyte hyperplasia, and reduce subcutaneous adipocyte mass.
Detailed explanation-2: -Adipose tissue regulates body temperature by providing a layer of insulation directly under the skin. The adipocyte cells in adipose tissue act to keep heat from escaping from the body too quickly.
Detailed explanation-3: -The cellular composition, secretome, and location of these adipose depots define their function in health and metabolic disease. In obesity, adipose tissue becomes dysfunctional, promoting a pro-inflammatory, hyperlipidemic and insulin resistant environment that contributes to type 2 diabetes mellitus (T2DM).
Detailed explanation-4: -In summary, these observations suggest that the age-related increase in histamine may act as a biomarker of increased mast cell accumulation in BAT, which in turn could exert inhibitory effects on brown adipocyte function. Aging results in mast cell accumulation which impairs brown adipogenesis.