AP PSYCHOLOGY

Detailed explanation-1: -Ventromedial nucleus of hypothalamus (VMH) has been designated as the satiety center [1]. Its stimulation causes cessation of eating in the animals, whereas bilateral lesions results in hyperphagia, polydypsia, increase in body weight and finickiness [2, 3].

Detailed explanation-2: -The ventromedial nucleus of the hypothalamus (VMH) is a complex brain structure that is integral to many neuroendocrine functions, including glucose regulation, thermogenesis, and appetitive, social, and sexual behaviors.

Detailed explanation-3: -The three parts of the hypothalamus that regulate food intake are called the ventromedial nuclei, the lateral hypothalamic area, and the arcuate nucleus. The ventromedial nuclei is the satiety center, and when stimulated, it causes the sensation of fullness.

Detailed explanation-4: -VMH is the important center for satiety and adiposity and could be the ultimate pathway for control of food intake and obesity. The mechanism of hyperphagia as a cause of increased body weight after VMH lesion could be the possible mechanism for obesity.

Detailed explanation-5: -Within the hypothalamus are nerve cells that, when activated, produce the sensation of hunger. They do so by producing two proteins that cause hunger: neuropeptide Y (NPY) and agouti-related peptide (AGRP). Quite close to these nerve cells is another set of nerves that powerfully inhibit hunger.