AP PSYCHOLOGY

Detailed explanation-1: -In short, melatonin helps you get to sleep and serotonin helps you feel awake when you get up the next day. A lack of melatonin can cause sleeplessness and even insomnia, whereas a deficiency in serotonin can result in feelings of depression and lethargy.

Detailed explanation-2: -Melatonin at a dosage of 0.5 mg/kg increased medial hypothalamic serotonin levels at 60 and 90 min after the injection. However, the dose of 1 mg/kg increased the levels of this amine or its metabolite in the preoptic area-anterior hypothalamus, medial and posterior hypothalamus, amygdala, and midbrain.

Detailed explanation-3: -Serotonin modulates melatonin synthesis as an autocrine neurotransmitter in the pineal gland.

Detailed explanation-4: -Low levels of serotonin may be associated with many health conditions including: Depression and other mood problems. Anxiety. Sleep problems.

Detailed explanation-5: -A common symptom of insufficient melatonin signaling is sleep disturbances. It is necessary to distinguish between symptoms that are curable by short melatonergic actions and others that require extended actions during night.