AP PSYCHOLOGY

Detailed explanation-1: -Methamphetamine-related cardiomyopathy is associated with severe systolic dysfunction, left ventricular chamber dilation. Clinical and autopsy reports obtained from long-term methamphetamine users showed indicators of cardiomyopathy, such as necrosis, fibrosis, hypertrophy, and enlargement of the heart.

Detailed explanation-2: -Shabu or syabu may refer to: Shabu, a slang term for the drug methamphetamine used in Japan, Hong Kong, Philippines, Malaysia and Indonesia. Ya ba, also called shabú (Philippines), pills with a mixture of methamphetamine and caffeine prevalent throughout Asia.

Detailed explanation-3: -Mechanism of Action Methamphetamine affects the central nervous system (CNS) by enhancing the release of monoamine neurotransmitters such as serotonin, dopamine, and norepinephrine. [4] The use of methamphetamine can lead to many pharmacological effects because of its ability to use various molecular processes.

Detailed explanation-4: -The pathophysiology of methamphetamine primarily relates to its effects on multiple neurotransmitter systems. Dopamine (DA), a catecholamine, is the major neurotransmitter impacted by methamphetamine use. However, methamphetamine also affects serotonergic, noradrenergic, and glutamatergic systems as well.