GENERAL HISTOLOGY

BONE

APPOSITIONAL

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The process of bone remodeling is ____
A
Continual addition of new bone tissue.
B
Continual resorption of old bone tissue.
C
Both the continual addition and resorption of bone tissue.
D
How a bone heals a fracture.
Explanation: 

Detailed explanation-1: -Bone tissue is continuously remodeled through the concerted actions of bone cells, which include bone resorption by osteoclasts and bone formation by osteoblasts, whereas osteocytes act as mechanosensors and orchestrators of the bone remodeling process.

Detailed explanation-2: -Bone remodeling (or bone metabolism) is a lifelong process where mature bone tissue is removed from the skeleton (a process called bone resorption) and new bone tissue is formed (a process called ossification or new bone formation).

Detailed explanation-3: -Bone remodelling is an active and dynamic process that relies on the correct balance between bone resorption by osteoclasts and bone deposition by osteoblasts. Moreover, these two functions must be tightly coupled not only quantitatively, but also in time and space.

Detailed explanation-4: -Bone remodeling is a two-part process involving both resorption and replacement of bone. Bone resorption is carried out by osteoclasts that break down the bone, whereas bone replacement is carried out by osteoblasts that add to the bone via secretion and mineralization of bone matrix.

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