GENERAL HISTOLOGY

Detailed explanation-1: -While bone is replacing cartilage in the diaphysis, cartilage continues to proliferate at the ends of the bone, increasing bone length. These proliferative areas become the epiphyseal plates (physeal plates/growth plates), which provide longitudinal growth of bones after birth and into early adulthood.

Detailed explanation-2: -Throughout childhood and adolescence, there remains a thin plate of hyaline cartilage between the diaphysis and epiphysis known as the growth or epiphyseal plate (Figure 6.4. 2f). Eventually, this hyaline cartilage will be removed and replaced by bone to become the epiphyseal line.

Detailed explanation-3: -Epiphyseal cartilage is hyaline cartilage tissue with a gelatinous texture, and it is responsible for the longitudinal growth of the long bones in birds and mammals. It is located between the epiphysis and the diaphysis. Epiphyseal cartilage also is called a growth plate or physis.

Detailed explanation-4: -Bone growth in length is primarily achieved through the action of chondrocytes in the proliferative and hypertrophic zones of the growth plate. Longitudinal growth is controlled by systemic, local paracrine and local mechanical factors.