GENERAL HISTOLOGY

Detailed explanation-1: -People with the disorder have a faulty gene that leads to weak collagen or not enough normal collagen in their tissues. These defects can harm the connective tissue’s ability to support muscles, organs, and other tissues.

Detailed explanation-2: -Disease Overview The problems seen in patients with EDS can be due to either the poor strength of collagen. It may alternatively be due to the absence of sufficient amounts of structurally normal collagen. The primary complications seen in EDS involve the skin, muscles, skeleton, and blood vessels.

Detailed explanation-3: -People who have Ehlers-Danlos syndrome usually have overly flexible joints and stretchy, fragile skin. This can become a problem if you have a wound that requires stitches, because the skin often isn’t strong enough to hold them.

Detailed explanation-4: -autosomal recessive inheritance (kyphoscoliotic EDS) – the faulty gene is inherited from both parents and there’s a 1 in 4 chance of each of their children developing the condition.