GENERAL HISTOLOGY

Detailed explanation-1: -Loose and dense connective tissue are made up of the following three fibers: collagen fibers, reticular fibers, and elastin fibers.

Detailed explanation-2: -The major components of all basement membranes are laminin, collagen IV, entactin/nidogen, and sulfated proteoglycans. Each of these describes a family of related proteins that assemble with each other in the extracellular space to form the basement membrane.

Detailed explanation-3: -Electron microscopy shows that the basement membrane consists of three layers: the lamina lucida (electron-lucent), lamina densa (electron-dense), and lamina fibro-reticularis (electron-lucent). The lamina densa was formerly called the “basal lamina”.

Detailed explanation-4: -Basement membrane is composed of a three-dimensional network of glycoproteins. The most abundant protein in the basement membrane is type IV collagen. Other components of the basement membrane are laminin, heparan sulfate proteoglycan, entactin, and fibronectin.