CONNECTIVE TISSUE GLAND
CONNECTIVE TISSUE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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presence of a prominent, clear area in the cytoplasm that is adjacent to the nucleus
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a large number of metachromatic granules with different density
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a large number of lysosomes and phagosomes
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well developed granular endoplasmic reticulum, Golgi complex and mitochondria
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a large number of small fat drops and mitochondria
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Detailed explanation-1: -The presence of cytoplasmic granules characterizes mast cells. Owing to the high acidity of the heparin in these granules, alkaline dyes undergo a change in color. This property, known as metachromasia, is unique to mast cells and basophils. The alkaline dye toluidine blue will stain secretory granules red-violet.
Detailed explanation-2: -They contain chemicals such as histamine, heparin, cytokines, and growth factors. They release these chemicals during allergic reactions and certain immune responses. These chemicals have many effects, including the widening of blood vessels and angiogenesis.
Detailed explanation-3: -Mast Cells are found close to small blood vessels in loose connective tissue. They contain large secretory granules of heparin proteoglycan-a weak anticoagulant. They also contain histamine, which promotes an inflammatory reaction when secreted.