GENERAL HISTOLOGY

CONNECTIVE TISSUE GLAND

CONNECTIVE TISSUE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What are the two main structures of the extracellular matrix
A
Ground substance and fibers
B
Ground substance and fluid
C
Fluid and fibers
D
None of the above
Explanation: 

Detailed explanation-1: -Connective tissue has three main components: cells, fibers, and ground substance. Together the ground substance and fibers make up the extracellular matrix. Connective tissue is classified into two subtypes: soft and specialized connective tissue.

Detailed explanation-2: -Extracellular matrix (ECM) is a non-cellular three-dimensional macromolecular network composed of collagens, proteoglycans/glycosaminoglycans, elastin, fibronectin, laminins, and several other glycoproteins.

Detailed explanation-3: -Fibroblasts (which secrete the fibers and ground substance of the extracellular matrix).

Detailed explanation-4: -Collagens, which constitute the main structural element of the ECM, provide tensile strength, regulate cell adhesion, support chemotaxis and migration, and direct tissue development (Rozario and DeSimone, 2010).

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