GENERAL HISTOLOGY

Detailed explanation-1: -Aldosterone (ALD) is a hormone your adrenal glands release that helps regulate blood pressure by managing the levels of sodium and potassium in your blood.

Detailed explanation-2: -Aldosterone, a steroid hormone, regulates renal Na+ reabsorption and, therefore, plays an important role in the maintenance of salt and water balance. In a model renal epithelial cell line (A6) we have found that phosphoinositide 3-kinase (PI 3-kinase) activity is required for aldosterone-stimulated Na+ reabsorption.

Detailed explanation-3: -Aldosterone is a steroid hormone synthesized in and secreted from the outer layer of the adrenal cortex, the zona glomerulosa. Aldosterone is responsible for regulating sodium homeostasis, thereby helping to control blood volume and blood pressure.

Detailed explanation-4: -Aldosterone causes an increase in salt and water reabsorption into the bloodstream from the kidney thereby increasing the blood volume, restoring salt levels and blood pressure.

Detailed explanation-5: -Aldosterone, the primary mineralocorticoid, is synthesized in the outer zone of the adrenal cortex called the zona glomerulosa (ZG). The production of aldosterone is tightly regulated by angiotensin II (Ang II) and circulating potassium levels.