GENERAL HISTOLOGY

Detailed explanation-1: -Growth hormone deficiency (GHD), also known as dwarfism or pituitary dwarfism, is a condition caused by insufficient amounts of growth hormone in the body. Children with GHD have abnormally short stature with normal body proportions. GHD can be present at birth (congenital) or develop later (acquired).

Detailed explanation-2: -Gigantism is abnormal growth due to an excess of growth hormone (GH) during childhood.

Detailed explanation-3: -Overproduction of hormones is also called hyperfunction or hypersecretion. Underproduction of hormones can be called hypofunction or hyposecretion. There are many reasons why endocrine glands send too much or too little of a needed hormone into your body. Sometimes this happens for genetic reasons.

Detailed explanation-4: -Over production of growth hormone leads to gigantism and its underproduction leads to dwarfism.

Detailed explanation-5: -Gigantism is usually caused by a non-cancerous tumour in the pituitary gland (called a benign adenoma) that produces too much growth hormone. Pituitary tumours can be small in size (micro-adenoma) or large (macro-adenoma). However, in gigantism, they are frequently large and invade nearby brain tissue.