GENERAL HISTOLOGY

Detailed explanation-1: -In type 2 diabetes, we believe that insulin binds to the receptor normally, but the signal is not sent into the cell, the cells do not take up glucose and the resulting high blood glucose levels cause organ damage over time.

Detailed explanation-2: -In type 1 diabetes, the pancreas (a small gland behind the stomach) progressively reduces the amount of insulin (the hormone that regulates blood glucose levels) it produces until it stops producing any at all. If the amount of glucose in the blood is too high, it can, over time, seriously damage the body’s organs.

Detailed explanation-3: -Insulin resistance is a problem found in people with prediabetes and type 2 diabetes, but it people with type 1 diabetes can become insulin resistant, too.

Detailed explanation-4: -In most people with type 1 diabetes, the body’s immune system, which normally fights infection, attacks and destroys the cells in the pancreas that make insulin. As a result, your pancreas stops making insulin. Without insulin, glucose can’t get into your cells and your blood glucose rises above normal.