ENDOCRINE SYSTEM
THYROID FOLLICULAR CELL
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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a storage area for iodine
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a storage site for T3 and T4
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a storage site for calcitonin
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a storage site for TSH
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Detailed explanation-1: -The stored hormone is bound to a glycoprotein, and this stored hormone is called ‘colloid’. This gland secretes iodine containing hormones called Tri-iodo thyronine (T3) and thyroxine (T4) of which T3 is more active. It regulates the basal metabolic rate, and it is regulated by the pituitary hormone TSH.
Detailed explanation-2: -Triodothyronine (T3) and thyroxine (T4) are stored in the colloid until TG is taken up by thyroid follicular cells through macro-and micropinocytosis and digested in lysosomes. Secretion of thyroid hormones then occurs into the bloodstream at the basolateral membrane.
Detailed explanation-3: -Thyroid hormone (T3 and T4) affects every cell and all the organs in your body by: Regulating the rate at which your body uses calories (energy). This affects weight loss or weight gain and is called the metabolic rate. Slowing down or speeding up your heart rate.
Detailed explanation-4: -Newly synthesized thyroid hormones (T3 and T4) are attached to thyroglobulin and comprise the colloid within the follicle. When stimulated by thyroid stimulating hormone (TSH), the colloid is endocytosed from the follicular lumen into the surrounding thyroid follicular epithelial cells.