GENERAL HISTOLOGY

EXCRETORY SYSTEM

KIDNEY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The concentration of urea is higher in urine than in the Bowman’s capsule?What is the reason for this?
A
Urea is added to the filtrate in the collecting duct
B
Urea is added to the filtrate in the loop of Henle
C
Urea is added to the filtrate in the proximal coiled tubule
D
Water is reabsorbed along the nephron
Explanation: 

Detailed explanation-1: -The urea reabsorbed increases the medullary concentration of the solute, which is critical for the reabsorption of water from the thin inner medullary part of the descending limb of the loop of Henle. Here, there is no osmotic gradient to cause water movement in the diluting kidney.

Detailed explanation-2: -Accumulation of urea is predominantly a result of passive urea reabsorption from the inner medullary collecting duct. Tubular fluid entering the collecting duct system in the renal cortex has a relatively low urea concentration.

Detailed explanation-3: -When passing through the renal tubules, a lot of substances and water is reabsorbed by making the filtrate concentrated. This is the point which generally returns in an increase in the concentration of urea as it is not reabsorbed by the body as water and glucose are.

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