GENERAL HISTOLOGY

EXCRETORY SYSTEM

KIDNEY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Why should glucose not appear in urine?
A
It is too large to be filtered through the Bowman’s capsule
B
It is rebsorbed in the collecting duct
C
It is rebsorbed in the distal convoluted tubule
D
It is rebsorbed in the proximal convoluted tubule
Explanation: 

Detailed explanation-1: -Reabsorption of glucose in the proximal convoluted tubule (PCT) reflects a critical property of this nephron segment-a high capacity relative to the normal filtered load of glucose (Figure 16-4).

Detailed explanation-2: -Usually, the urine does not contain sugar. This is because the kidneys reabsorb it from the blood as it passes through the body. Glycosuria occurs when the urine contains more glucose than it should. When there is too much glucose in the blood, the kidneys may not be able to reabsorb it all.

Detailed explanation-3: -Under normal circumstances, up to 180 g/day of glucose is filtered by the renal glomerulus and virtually all of it is subsequently reabsorbed in the proximal convoluted tubule. This reabsorption is effected by two sodium-dependent glucose cotransporter (SGLT) proteins.

Detailed explanation-4: -The glucose that enters the nephron along with the filtrate get absorbed by the glomerulus goes to the proximal convoluted tubule (pct) and again reabsorbed and enters the blood.

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