GENERAL HISTOLOGY

Detailed explanation-1: -The stratum granulosum contains the last layer of living cells, and these cells contain protein-filled granules that promote keratin crosslinking. The stratum lucidum are layers of dead cells that exocytosed lamellar bodies, which are rich in lipids, and aid in the skin’s barrier function.

Detailed explanation-2: -The stratum corneum is the outermost layer of the epidermis, and is made up of 10 to 30 thin layers of continually shedding, dead keratinocytes.

Detailed explanation-3: -Cells are pushed into stratum granulosum and become flattened and diamond shaped. The cells accumulate keratohyalin granules mixed between tonofibrils. Cells continue to stratum corneum where they flatten and lose organelles and nuclei. The keratohyalin granules turn tonofibrils into a homogenous keratin matrix.