GENERAL HISTOLOGY

Detailed explanation-1: -Stratum basale, also known as stratum germinativum, is the deepest layer, separated from the dermis by the basement membrane (basal lamina) and attached to the basement membrane by hemidesmosomes.

Detailed explanation-2: -The two primary functions of the stratum basale are 1) proliferation and 2) attachment of the epidermis to the dermis. Cells of the stratum basale essentially represent germinal cells (“brick generators”) responsible for the generation of all cells of the epidermis.

Detailed explanation-3: -The basal cell layer (stratum basale, or stratum germinosum), is a single layer of cells, closest to the dermis. It is usually only in this layer that cells divide. Some of the dividing cells move up to the next layer. The prickle cell layer (stratum spinosum) is the next layer (8-10 layers of cells).