GENERAL HISTOLOGY

Detailed explanation-1: -What particular cell structures can be observed using an electron microscope? The nucleus, cell wall, vacuoles, endoplasmic reticulum, Golgi Apparatus, ribosomes, and mitochondria are some of the easily visible structures of the cell when viewed through an EM.

Detailed explanation-2: -Two types of electron microscopy-transmission and scanning-are widely used to study cells. In principle, transmission electron microscopy is similar to the observation of stained cells with the bright-field light microscope.

Detailed explanation-3: -Thus, light microscopes allow one to visualize cells and their larger components such as nuclei, nucleoli, secretory granules, lysosomes, and large mitochondria. The electron microscope is necessary to see smaller organelles like ribosomes, macromolecular assemblies, and macromolecules.

Detailed explanation-4: -A transmission electron microscope would be ideal for viewing the cell’s internal structures, because many of the internal structures have membranes that are not visible by the light microscope.