GENERAL HISTOLOGY

Detailed explanation-1: -Bile salts are not digestive enzymes but contains inorganic salts. They neutralize the HCl, imparting alkanity to chyme and inactivating gastric pepsin. Here, the fat is emulsified, which facilitates easy action of lipases of pancreatic juice upon the fat.

Detailed explanation-2: -Emulsification: In the small intestine lipids are emulsified by bile salts. Bile salts (bile salts = conjugation of bile acids with taurine or glycine) are polar and water soluble and function as detergents whereby they emulsifies larger fats into smaller droplets.

Detailed explanation-3: -Emulsification is possible due to the amphipathic property of bile salts [1]. The hydrophilic portion of the bile salts surrounds the lipid, forcing the lipid to disperse as the negative charges repel each other. Bile salts also allow the products of lipid digestion to be transported as micelles.

Detailed explanation-4: -Bile contributes to digestion by breaking up large fat globules, a process known as emulsification. Fats are insoluble in water, so emulsification provides pancreatic lipase with more surface area on which to act.

Detailed explanation-5: -Emulsification in digestion is the breakdown of fat globules in the duodenum into small droplets creating a larger area where the pancreatic lipase enzyme can work to digest the fat into fatty acids and glycerol. The activity of the bile salts helps to emulsify the fats.