GENERAL HISTOLOGY

Detailed explanation-1: -Nitrogenous waste which is less toxic, soluble in water and formed during the Ornithine cycle is urea. Urea is the excretory product of mammals which is soluble in water and less toxic. Ornithine cycle is also known as urea cycle in which urea is formed from ammonia by some chemical reactions.

Detailed explanation-2: -Urea, the principal nitrogenous waste product of amphibians and mammals, is synthesized in the liver from ammonia and carbon dioxide by a sequence of reactions known as the urea cycle or ornithine cycle.

Detailed explanation-3: -Uric acid is the least harmful among ammonia and urea. It has no harmful effects when retained in cells and bodily tissues. In comparison to the other two modes of excretion, it is the most efficient.