LYMPHATIC
LYMPHATIC SYSTEM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The organ where T cells complete their development is called the ____
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lymph
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tissue fluid
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lymph node
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thymus
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spleen
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Explanation:
Detailed explanation-1: -In the case of T cells, development is compartmentalized, with different types of stromal cells in the thymic cortex and medulla. Most steps in T-cell differentiation occur in the cortex of the thymus. The thymic medulla contains mainly mature T cells.
Detailed explanation-2: -The thymus is the primary site of T cell development, where progenitors from the bone marrow lacking CD4+ and CD8+ coreceptor expression undergo T cell receptor (TCR) rearrangement to generate CD4+CD8+ double positive (DP) thymocytes.
Detailed explanation-3: -T cells are derived from haematopoietic stem cells that are found in the bone marrow. The progenitors of these cells migrate to and colonise the thymus.
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