GENERAL HISTOLOGY

Detailed explanation-1: -Peyer’s patches (PPs) are a series of small lymphoid organs situated in the wall of the small intestine.

Detailed explanation-2: -The gut-associated lymphoid tissue (GALT) consists of isolated or aggregated lymphoid follicles forming Peyer’s patches (PPs). By their ability to transport luminal antigens and bacteria, PPs can be considered as the immune sensors of the intestine.

Detailed explanation-3: -Microscopically, Peyer’s patches appear as oval or round lymphoid follicles (similar to lymph nodes) located in the mucosa layer of the ileum and extend into the submucosa layer. The number of Peyer’s patches peaks at age 15–25 and then declines during adulthood.