GENERAL HISTOLOGY

Detailed explanation-1: -The thymus gland is most active during childhood. Your thymus actually starts making T-cells before you’re born. It keeps producing T-cells and you have all the T-cells you need by the time you reach puberty. After puberty, your thymus gland slowly starts to decrease in size and is replaced by fat.

Detailed explanation-2: -The thymus gland, located behind your sternum and between your lungs, is only active until puberty. After puberty, the thymus starts to slowly shrink and become replaced by fat. Thymosin is the hormone of the thymus, and it stimulates the development of disease-fighting T cells.

Detailed explanation-3: -Hypothetically, the thymus should stop functioning at around 105 years of age; but, studies with bone marrow transplant patients have shown that the thymi of the majority of patients over forty were unable to build a naïve T cell compartment.

Detailed explanation-4: -The thymus is a vital yet unusual organ. Vital in that it is responsible for producing immune cells; unusual in that it is largest at childhood and progressively shrinks after puberty. The result is less T cell production, which should lead to a higher risk of infection or cancer.