GENERAL HISTOLOGY

Detailed explanation-1: -The sarcolemma is the plasma membrane of the muscle cell and is surrounded by basement membrane and endomysial connective tissue. The sarcolemma is an excitable membrane and shares many properties with the neuronal cell membrane.

Detailed explanation-2: -The sarcolemma maintains the intracellular milieu, actively transports substrates into the muscle cell, serves as a docking location for proteins originating in the basement membrane and cytoskeleton, and also transmits neural excitatory impulses that lead to muscle contraction.

Detailed explanation-3: -The sarcolemma is the plasma membrane. The sarcolemma is described as having two layers. The first is the plasma membrane, which is a structure of similar biochemical composition to the general plasma membrane found in eukaryotic cells. The second layer is the glycocalyx, which is in contact with the basement membrane.

Detailed explanation-4: -The sarcolemma transmits force and is subjected to substantial stress during contractions (48). The sarcolemma is linked to the contractile apparatus by a membrane-associated cytoskeleton, which contains proteins that have also been implicated in force transmission and have been described in several reviews (41, 50).