GENERAL HISTOLOGY

MUSCLE

SKELETAL MUSCLE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What protein is wrapped around actin that prevents it from contacting myosin
A
Troponin
B
Tropomyosin
C
Calcium
D
None of the above
Explanation: 

Detailed explanation-1: -The TN-T component attaches the complex to tropomyosin at intervals along the thin myofilaments. With low sarcoplasmic calcium concentrations (10−7 M), tropomyosin molecules block the myosin-binding sites on actin, which prevents the interaction of actin and myosin.

Detailed explanation-2: -Thin Filaments The actin molecules contain active sites to which myosin heads will bind during contraction. The thin filaments also contain the regulatory proteins called tropomyosin and troponin, which regulate the interaction of actin and myosin.

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