GENERAL HISTOLOGY

MUSCLE

SKELETAL MUSCLE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The heads of the myosin filaments are called ____ when they link the thin and thin filaments together
A
Connections
B
Cross-connections
C
Cross-bridges
D
Power stroke
Explanation: 

Detailed explanation-1: -The globular heads of myosin bind actin, forming cross-bridges between the thick and thin filaments.

Detailed explanation-2: -Cross-bridge formation occurs when the myosin head attaches to the actin while adenosine diphosphate (ADP) and inorganic phosphate (Pi) are still bound to myosin (Figure 4a, b).

Detailed explanation-3: -If the actin binding sites are uncovered, a cross-bridge will form; that is, the myosin head spans the distance between the actin and myosin molecules. Pi is then released, allowing myosin to expend the stored energy as a conformational change. The myosin head moves toward the M line, pulling the actin along with it.

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