GENERAL HISTOLOGY

Detailed explanation-1: -Celiac disease is a chronic digestive and immune disorder that damages the small intestine. The disease is triggered by eating foods containing gluten. The disease can cause long-lasting digestive problems and keep your body from getting all the nutrients it needs.

Detailed explanation-2: -If you have celiac disease, eating gluten triggers an immune response in your small intestine. Over time, this reaction damages your small intestine’s lining and prevents it from absorbing some nutrients (malabsorption).

Detailed explanation-3: -Patients with celiac disease who ingest any wheat products develop abnormalities in the lining of the small intestine, particularly the upper part (jejunum).

Detailed explanation-4: -Gluten. Consuming gluten triggers the abnormal immune system response that causes celiac disease. However, not all people who have the gene variants DQ2 or DQ8 and eat gluten develop the disease.

Detailed explanation-5: -Celiac disease is also called celiac sprue, nontropical sprue, and gluten-sensitive enteropathy.