GENERAL HISTOLOGY

VASCULAR

THE NEPHRON

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
To enter the Bowman’s capsule, fluid from the blood crosses (in the correct order) ____
A
epithelium of Bowman’s capsule, basement membrane, capillary endothelium
B
capillary endothelium, epithelium of Bowman’s capsule, basement membrane
C
arteriole endothelium, basement membrane, epithelium of Bowman’s capsule
D
capillary endothelium, basement membrane, epithelium of Bowman’s capsule
Explanation: 

Detailed explanation-1: -The sequence of layers through which the filtration of blood takes place in the nephron is as follows: The endothelium of glomerular blood vessels, basement membrane and the epithelium of Bowman’s capsule having cells called podocytes . Q. Protein-free fluid is filtered from blood plasma into the Bowmans capsule.

Detailed explanation-2: -Any small molecules such as water, glucose, salt (NaCl), amino acids, and urea pass freely into Bowman’s space, but cells, platelets and large proteins do not.

Detailed explanation-3: -Liquid and solutes of the blood must pass through multiple layers to move from the glomerular capillaries into Bowman’s space to ultimately become filtrate within the nephron’s lumen. Following the GBM, filtrate must pass through the epithelial layer of Bowman’s capsule, which is composed of podocytes.

Detailed explanation-4: -Hence the correct order is ‘Glomerular filtration → Reabsorption → Secretion’.

There is 1 question to complete.