VASCULAR
THE NEPHRON
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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When the active site is working fine
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when the active site has grown too big
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when the active site has changed shape due to damage
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when the active site has all been used up
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Detailed explanation-1: -This means that the 3D confirmation is altered and the shape of the active site becomes irreversibly changed. Now that we have discussed denaturation in detail, let’s look back at our question. We now know that the correct answer is (D). “Denatured” means that the enzyme’s active site has been irreversibly changed.
Detailed explanation-2: -When an enzyme is denatured, these bonds holding the enzyme together are disrupted, leading to a loss of structure. Depending on the degree of denaturation, only the active site of the enzyme might be affected, reducing the ability for the enzyme to effectively bind to its substrate.
Detailed explanation-3: -Denaturation is caused by the breaking of the bonds that hold the enzyme together in its three-dimensional shape. Heat can break hydrogen and ionic bonds, which disrupts the shape of the enzyme and will change the shape of the active site.