MRCP UK EXAMINATIONS

ABDOMINAL

GASTROINTESTINAL

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Biopsies are taken from the antra and duodenal mucosa of a 65-year-old woman. which of the following hormones can be found in tissue homogenates from both locations?
A
Cholecystokinin (CCK)
B
Gastrin
C
Motilin
D
Secretin
Explanation: 

Detailed explanation-1: -In the lower gastrointestinal tract, an enterogastrone is a hormone that is secreted by the mucosa of the duodenum. Enterogastrone hormones are in charge of preventing gastric secretion and limiting stomach motility.

Detailed explanation-2: -The presence of fat, such as oleate, in the meal results in stimulation of cholecystokinin (CCK) secretion in the duodenum; in turn, this inhibits antral motility, stimulates pyloric tone and delays gastric emptying [8]. CCK is the first of a repertoire of hormones that regulate gastric emptying.

Detailed explanation-3: -Secretin is a peptide hormone produced in the S cells intestinal gland of the duodenum. It inhibits the secretion of gastric acid from the parietal cells of the stomach thereby helps in regulating the pH of duodenum.

There is 1 question to complete.