MRCP UK EXAMINATIONS

Detailed explanation-1: -Two types of heparins are widely used, unfractionated heparin (UFH) and low molecular weight heparin (LMWH). Heparin‐induced thrombocytopenia (HIT) is an adverse reaction that can occur during treatment with heparin.

Detailed explanation-2: -The only statistically significant difference between the two heparins was a larger haematoma formation at heparin injection sites when calcium heparin was used. Otherwise sodium-and calcium-heparin are equal in effect and side effects provided they come from the same heparin source.

Detailed explanation-3: -The calcium salt form of heparin. As a glycosaminoglycan anticoagulant, heparin calcium binds to antithrombin III to form a heparin-antithrombin III complex.

Detailed explanation-4: -There are two types of heparins: high molecular weight heparins and low molecular weight heparins. High molecular weight heparins require daily blood monitoring to check the aPTT. Low molecular weight heparins give a better anticoagulant response and do not need daily blood monitoring.

Detailed explanation-5: -Lovenox generic name, enoxaparin manufactured by Sanofi-Aventis. Fragmin generic name, dalteparin manufactured by Pfizer. Innohep generic name, tinzaparin manufactured by Celgene. 06-Feb-2018