AP PSYCHOLOGY

Detailed explanation-1: -A metabotropic receptor, also referred to by the broader term G-protein-coupled receptor, is a type of membrane receptor that initiates a number of metabolic steps to modulate cell activity. The nervous system utilizes two types of receptors: metabotropic and ionotropic receptors.

Detailed explanation-2: -Metabotropic receptors are monomeric proteins with an extracellular domain that contains a neurotransmitter binding site and an intracellular domain that binds to G-proteins.

Detailed explanation-3: -Metabotropic receptors act either directly or indirectly as signal transduction enzymes, or are linked to enzymes that have an extracellular domain recognizing a drug and an intracellular domain that catalyzes a biochemical response.

Detailed explanation-4: -G-protein-coupled receptors (GPCRs), also called metabotropic receptors, are membrane-bound proteins that activate G-proteins after binding neurotransmitters.

Detailed explanation-5: -A Metabotropic Receptor is a G-protein-coupled receptor. The term reflects the fact that transmitter binding results in the production of intracellular metabolites.