AP PSYCHOLOGY

Detailed explanation-1: -Just as heroin or morphine and cocaine activate the reward pathway in the VTA and nucleus accumbens, other drugs such as nicotine and alcohol activate this pathway as well, although sometimes indirectly (point to the globus pallidus, an area activated by alcohol that connects to the reward pathway).

Detailed explanation-2: -All addictive drugs affect brain pathways involving reward-that is, the dopamine system in the reward pathway. Within seconds to minutes of entering the body, drugs cause dramatic changes to synapses in the brain. By activating the brain’s reward circuitry, drugs deliver a jolt of intense pleasure.

Detailed explanation-3: -Research has shown that the drugs most commonly abused by humans (including opiates, alcohol, nicotine, amphetamines, and cocaine) create a neurochemical reaction that significantly increases the amount of dopamine that is released by neurons in the brain’s reward center.

Detailed explanation-4: -The most important reward pathway in brain is the mesolimbic dopamine system, composed of the VTA (ventral tegumental area) and NAc (nucleus accumbens). This (VTA-NAc) circuit is a key detector of a rewarding stimulus.