AP PSYCHOLOGY

Detailed explanation-1: -IRBs are charged with providing an independent evaluation that proposed research is ethically acceptable, checking clinical investigators’ potential biases, and evaluating compliance with regulations and laws designed to protect human subjects.

Detailed explanation-2: -Yes, investigators are responsible for obtaining IRB approval before beginning any nonexempt human subjects research (45 CFR 46.109(a) and (d)).

Detailed explanation-3: -Under FDA regulations, an IRB is an appropriately constituted group that has been formally designated to review and monitor biomedical research involving human subjects. In accordance with FDA regulations, an IRB has the authority to approve, require modifications in (to secure approval), or disapprove research.

Detailed explanation-4: -An IRB must have at least one scientist member and at least one member whose primary concerns are nonscientific. Additionally, there must be one member who is not otherwise affiliated with the institution (a community representative).

Detailed explanation-5: -What is an Institutional Review Board (IRB) and why is it necessary for research? An Institutional Review Board is a group of individuals charged with reviewing proposed research involving human subjects to protect those subjects and ensure compliance with federal human subjects regulations.