HUMAN NUTRITION

Detailed explanation-1: -Duodenum. The duodenum is the first part of the small intestine that the stomach feeds into. It’s a short, descending chute (about 10 inches long) that curves around the pancreas in a “C” shape before connecting to the rest of the coiled intestines.

Detailed explanation-2: -The intestines fulfill an important role in drug metabolism, and it is known that the expression levels of the involved enzymes differ along the intestinal tract.

Detailed explanation-3: -Most drugs must pass through the liver, which is the primary site for drug metabolism. Once in the liver, enzymes convert prodrugs to active metabolites or convert active drugs to inactive forms. The liver’s primary mechanism for metabolizing drugs is via a specific group of cytochrome P-450 enzymes.