HUMAN NUTRITION

Detailed explanation-1: -It is caused by a buildup of plaque in the inner lining of an artery. Plaque is made up of deposits of fatty substances, cholesterol, cellular waste products, calcium, and fibrin. As it builds up in the arteries, the artery walls become thickened and stiff.

Detailed explanation-2: -Role of lipids in the pathophysiology of atherosclerosis Because lipids are insoluble in plasma, circulating lipids are bound to lipoproteins and transported to various tissues where they are used for various functions including energy utilisation, synthesis of steroid hormones, and bile acid formation.

Detailed explanation-3: -If the blockage occurs in an artery of the heart (coronary artery), it will cause angina (chest pain). As it progresses, atherosclerosis in the arteries of the heart may cause a heart attack or if it develops in the brain, it can cause a stroke.