HUMAN NUTRITION

Detailed explanation-1: -In the lock-and-key model, the enzyme-substrate interaction suggests that the enzyme and the substrate possess specific complementary geometric shapes that fit exactly into one another.

Detailed explanation-2: -enzymes. …and enzyme, called the “key–lock” hypothesis, was proposed by German chemist Emil Fischer in 1899 and explains one of the most important features of enzymes, their specificity.

Detailed explanation-3: -The mechanism of action of enzyme inhibitors includes a step of enzyme-inhibitor complex formation (EI complex) that has no (or low) enzyme activity. An irreversible inhibitor dissociates from this complex very slow because it is tightly bound to the enzyme.