HUMAN NUTRITION

NUTRITION

SPORTS NUTRITION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
which of the following sugars is the most lipogenic ( most readily converted into body fat)?
A
Transfats
B
Oil
C
Glucose
D
Fructose
Explanation: 

Detailed explanation-1: -Unlike glucose, ingested fructose is preferentially metabolized by the liver [30]. This and several other features of fructose metabolism make it an exceptionally lipogenic sugar [20, 29, 31]. In this review, we will focus on the role of fructose consumption in the development of hepatic steatosis.

Detailed explanation-2: -While glucose is the main substrate for DNL, fructose is a highly lipogenic substrate (Dekker et al., 2010) and this is thought to arise from it bypassing the critical regulatory step catalysed by phosphofructokinase‐1 (PFK‐1) in glycolysis (Basaranoglu, 2013).

Detailed explanation-3: -Several properties of fructose metabolism make it particularly lipogenic. Fructose is absorbed via portal vein and delivered to the liver in much higher concentrations as compared to other tissues. Fructose increases protein levels of all DNL enzymes during its conversion into triglycerides.

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