HUMAN NUTRITION

Detailed explanation-1: -Acrodermatitis enteropathica (AE) is an inherited form of zinc deficiency caused by a defect in the absorption of zinc. Zinc is a very important micronutrient, a component of more than two-hundred metalloenzymes, and essential for the proper functioning of the various metabolic and biochemical pathways of the body.

Detailed explanation-2: -Acute zinc deficiency disorder is characterized by dermatitis around the limbs and body orifices, diarrhea, and impaired immune function, whereas chronic zinc deficiency disorder can lead to liver or kidney failure (2).

Detailed explanation-3: -The clinical manifestations of acquired zinc deficiency and AE are similar and consist of 3 essential symptoms: periorificial dermatitis, alopecia, and diarrhea. This clinical triad is complete in only 20% of patients with AE.