HUMAN NUTRITION

Detailed explanation-1: -It is formed from the breakdown of a larger protein, called amyloid precursor protein. One form, beta-amyloid 42, is thought to be especially toxic. In the Alzheimer’s brain, abnormal levels of this naturally occurring protein clump together to form plaques that collect between neurons and disrupt cell function.

Detailed explanation-2: -Researchers believe that in early Alzheimer’s disease, a protein called tau builds up in the brain cells and forms tangles which ultimately make the brain cell sick and die.

Detailed explanation-3: -How Do Plaques and Tangles Cause Dementia? The presence of plaques around a neuron causes them to die, possibly by triggering an immune response in the immediate area. Tangles form inside of neurons and interfere with the cellular machinery used to create and recycle proteins, which ultimately kills the cell.

Detailed explanation-4: -Rogue Proteins – Plaques & Tangles Amyloid plaques are the gradual buildup and accumulation of protein fragments between neurons; these form when Alzheimer’s disrupts the brain’s normal disposal process for the proteins, eventually impacting cognitive function.