AP BIOLOGY

Detailed explanation-1: -The mitotic spindle is a microtubule-made machine required for chromosome segregation during mitosis. Several pathways and molecules contribute to the assembly of this structure, which shows intrinsic dynamic properties.

Detailed explanation-2: -The segregation of the replicated chromosomes is brought about by a complex cytoskeletal machine with many moving parts-the mitotic spindle. It is constructed from microtubules and their associated proteins, which both pull the daughter chromosomes toward the poles of the spindle and move the poles apart.

Detailed explanation-3: -The spindle is built of microtubules that are used as tracks to move chromosomes precisely during cell division. In the spindle, microtubules are arranged in two antiparallel arrays with their plus ends at the equator and their minus ends at the poles, whatever the detailed shape of the spindle (Fig.