THE HUMAN IMMUNE SYSTEM
TRANSFUSION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which of the following is not a sensitive test for detecting IMHA?
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Spherocytosis
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Positive SAT (saline agglutination test)
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Hemoglobinemia
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Direct Coombs’ test
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Explanation:
Detailed explanation-1: -Coombs test is necessary when autoimmunity to red blood cells is a consideration in the differential diagnosis, including warm and cold hemolytic anemia. Following are some indications where antiglobulin testing becomes useful: Autoimmune hemolytic anemia.
Detailed explanation-2: -To diagnose hemolytic anemia, your doctor will do a physical exam and order blood tests. Additional tests may include a urine test, a bone marrow test, or genetic tests.
Detailed explanation-3: -Osmotic fragility test. This test looks for red blood cells that are more fragile than normal. These cells may be a sign of hereditary spherocytosis (an inherited type of hemolytic anemia).
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