AP BIOLOGY

Detailed explanation-1: -When uric acid is formed from ammonia in the liver it is known as an inosinic pathway. Uric acid is formed as the end result of breakdown of purines. When degradation of purine occurs it leads to the formation of inosinic acid. Inosinic acid is also released due to the deamination of adenine as it is also a purine.

Detailed explanation-2: -Inosinic acid is important in metabolism. It is the ribonucleotide of hypoxanthine and the first nucleotide formed during the synthesis of purine nucleotides.

Detailed explanation-3: -The urea cycle (also known as the ornithine cycle) is a biochemical reaction cycle in which ammonia is converted to urea.

Detailed explanation-4: -The Ionosinic pathway is the pathway that involves the synthesis of inosine acid or inosine monophosphate (IMP). It is the first nucleotide formed (as an intermediate) during the synthesis of purine. In the liver, ammonia combines with carbon dioxide and ATP to form urea. Urea synthesis is a five-step cyclic process.

Detailed explanation-5: -Conversion of ammonia into uric acid occurs through Ionosinic pathway.