AP BIOLOGY

Detailed explanation-1: -The dialysate concentration of glucose is commonly between 100 and 200 mg/dL. Freshly prepared dialysate solution circulates continuously to the dialyzer in the extracorporeal circuit. After making a single pass through the dialyzer, the effluent dialysate goes to the drain.

Detailed explanation-2: -During haemodialysis, plasma glucose diffuses across the concentration gradient from the blood to the dialysate. In addition, the plasma glucose level at the post-dialyser site decreases to less than the glucose concentration of the dialysate, possibly as a result of diffusion of plasma glucose into erythrocytes.

Detailed explanation-3: -Abstract. Hemodialysate solutions often contain high concentrations of glucose (up to 200 mg/dL). The historical reasons for the addition of glucose to the dialysate included: (1) aid in performance of ultrafiltration and (2) minimization of nutritional (caloric) losses during dialysis.

Detailed explanation-4: -As the dialysis fluid contains a glucose concentration equal to a normal blood sugar level, this prevents the net movement of glucose across the membrane as no concentration gradient exists. This is very important as the patients’ need to retain glucose for respiration.