AP BIOLOGY

Detailed explanation-1: -During prophase, the nucleus disappears, spindle fibers form, and DNA condenses into chromosomes (sister chromatids). During metaphase, the sister chromatids align along the equator of the cell by attaching their centromeres to the spindle fibers.

Detailed explanation-2: -Metaphase. During metaphase, spindle fibers attach to the centromere of each pair of sister chromatids (see Figure below). The sister chromatids line up at the equator, or center, of the cell. This is also known as the metaphase plate.

Detailed explanation-3: -Anaphase: During anaphase, the centromere splits, allowing the sister chromatids to separate. The kinetochore spindle fibers shorten, allowing for 46 of the newly-freed chromatids to be dragged to one end of the cell and the remaining 46 chromatids to be dragged to the opposite end of the cell.

Detailed explanation-4: -Metaphase follows prophase. During metaphase, the chromosomes align in the center of the cell at the equatorial plate and the spindle fibers attach to the centromeres of the chromosomes.

Detailed explanation-5: -During prophase, the chromosomes condense and the nucleolus disappears. At the beginning of prophase, the chromosomes are condensing to become visible microscopically. Each chromosome consists of two parallelsister chromatids, joined together at one point along their length at thecentromere.