AP BIOLOGY

Detailed explanation-1: -Regeneration and wound healing are complex processes that allow organs and tissues to regain their integrity and functionality after injury. Wound healing, a key property of epithelia, involves tissue closure that in some cases leads to scar formation.

Detailed explanation-2: -All dermal wounds heal by three basic mechanisms: contraction, connective tissue matrix deposition and epithelialization. Wounds that remain open heal by contraction; the interaction between cells and matrix results in movement of tissue toward the center of the wound.

Detailed explanation-3: -New approaches to healing. Regenerative medicine is focused on developing and applying new treatments to heal tissues and organs and restore function lost due to aging, disease, damage or defects. The human body has the natural ability to heal itself in many ways.

Detailed explanation-4: -Tissue regeneration involves cell recruitment, growth, proliferation and differentiation, with the latter representing a crucial stage for the success of regeneration, avoiding the formation of fibrous tissue characteristic of the repair [9-12].

Detailed explanation-5: -The closure of a skin wound can be realized by regeneration or repair. While regeneration describes the specific substitution of the tissue, i.e. the superficial epidermis, mucosa or fetal skin, skin repair displays an unspecific form of healing in which the wound heals by fibrosis and scar formation.