BIOCHEMISTRY
ENZYMES AND METABOLISM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Detailed explanation-1: -NADH enters the ETC at complex I and produces a total of 10 H+ ions through the ETC (4 from complex I, 4 from complex III, and 2 from complex IV).
Detailed explanation-2: -All the components of the chain are embedded in or attached to the inner mitochondrial membrane. In the matrix, NADH deposits electrons at Complex I, turning into NAD+ and releasing a proton into the matrix. FADH2 in the matrix deposits electrons at Complex II, turning into FAD and releasing 2 H+.
Detailed explanation-3: -NADH is oxidized back to NAD+. The electrons from NADH are transferred coenzyme Q, a non-polar electron carrier. The membrane must be fluid for it to diffuse from one complex to the next. Four protons are pumped from the inside (matrix) to the intermembrane space for each pair of electrons processed.
Detailed explanation-4: -The oxidation of one molecule of NADH thus leads to the synthesis of three molecules of ATP, whereas the oxidation of FADH2, which enters the electron transport chain at complex II, yields only two ATP molecules.
Detailed explanation-5: -Inside the mitochondria, one molecule of NADH is equivalent to 3 ATP.