BIOCHEMISTRY
ENZYMES AND METABOLISM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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reductive amination, amidation
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reductive amination, amination
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reductive amination, transamination
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non of above
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Detailed explanation-1: -Glutamine synthetase (E.C. 6.3. 1.2), referred to for brevity as GS, catalyzes the amidation of glutamate to glutamine. Glutamine is of major importance in a variety of biosynthetic pathways including the synthesis of proteins, mucopolysaccharides, and nucleic acids (Meister, 1974).
Detailed explanation-2: -Reductive amination is the process in which ammonia reacts with alpha-ketoglutaric acid and forms glutamic acid in the presence of enzyme glutamate dehydrogenase.
Detailed explanation-3: -Glutamate is of central importance in plant N metabolism since the biosynthesis of all other amino acids requires this compound. Glutamate dehydrogenase (GDH; EC 1.4. 1.2), which catalyzes in vitro reversible reductive amination of 2-oxoglutatre to form glutamate, is a key player in the metabolism of glutamate.
Detailed explanation-4: -So, the correct answer is ‘Glutamine’.