BIOCHEMISTRY
ENZYMES AND METABOLISM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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They flip back and forth across the membrane to access target proteins on either side.
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They require phospholipids as a cofactor.
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They can more readily encounter and phosphorylate other membrane proteins.
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Membrane localization lowers the activation energy of the phosphorylation reaction.
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Detailed explanation-1: -Protein kinases are enzymes that transfer the terminal phosphate from ATP to an amino acid residue on the target protein. Many are located on the plasma membrane as integral membrane proteins or peripheral membrane proteins.
Detailed explanation-2: -Protein kinases are enzymes that catalyze the transfer of the -phosphate of ATP to the protein substrates, thus altering their functions.
Detailed explanation-3: -Protein kinases are enzymes that transfer a phosphate group from a molecule of ATP onto a protein or other substrate. This activity, known as ‘phosphorylation’, is important for a wide range of cellular processes.
Detailed explanation-4: -In biochemistry, a kinase (/ˈkaɪneɪs, ˈkɪneɪs, -eɪz/) is an enzyme that catalyzes the transfer of phosphate groups from high-energy, phosphate-donating molecules to specific substrates.